Autoimmune thyroiditis
Autoimmune thyroiditis (Hashimoto's thyroiditis) is an autoimmune lesion of the thyroid gland, leading to progressive tissue destruction and the development of thyroid hormone deficiency.
Autoimmune thyroiditis is the leading cause of hypothyroidism. The disease is associated with the synthesis of autoantibodies to thyroid tissue antigens in the body, which induce inflammation in it, leading to lymphocytic infiltration, resulting in tissue destruction, followed by replacement of functional tissue with connective tissue structures.
As a rule, autoimmune thyroiditis has a long gradual development from an euthyroid state to the outcome of severe hypothyroidism. Often, the development of thyroiditis can take years or even decades, manifesting for a long time with nonspecific symptoms determined by subclinical hypothyroidism and an insidious ongoing polyglandular syndrome (a combination of hormonal insufficiency from several glands - thyroid, pancreas, and adrenal glands).
Polyglandular insufficiency - in most clinical cases, a sluggish autoimmune disease, determined by the gradual "failure" of endocrine organs.
Treatment of hypothyroidism, like hypofunction of other endocrine organs, as a rule, comes down to prescribing permanent hormone replacement therapy.
However, this is a classic but far from optimal path. Hormone replacement therapy is often a necessary component that compensates for the formed hormone deficiency, but it does not stop the progression of the autoimmune process and the further progression of the disease.
Read more about the development of autoimmune diseases in the book by V.O. Generalov "The Pyramid of Health"
That is why autoimmune thyroiditis should be considered as part of a systemic autoimmune process. This means that its treatment, compensation, and maintenance of remission should be approached comprehensively.