About the course
Authors and lecturers:
Obodzinskaya Tatyana Evgenievna - psychiatrist, psychotherapist, hypnotherapist, member of ASCOG. Specialist in preventive and integrative medicine. Author of methodological manuals on clinical biochemistry and metabolomics.
Neuroinflammation underlies most known chronic and acute neurodegenerative diseases of the central nervous system. The neuroinflammatory response arises to adapt damaged tissue (for example, after trauma, exposure to a toxic or infectious agent, etc.), restore homeostasis, and activate regeneration processes.
The duration and uncontrollability of the neuroinflammatory process lead to a cascade of aggressive biochemical reactions that damage nervous system cells. The biochemical and metabolic processes underlying neuroinflammation are accessible for monitoring and correction.
In our educational course, we examine in detail the biochemical and metabolic foundations of the development of neuroinflammatory reactions and damage to the central nervous system, review laboratory tests of amino acids and organic acids, their interpretation, and methods of correction.
Program:
- Lecture 1. The concept of metabolic acidosis, causes of lactic acid accumulation in the human body, routes of elimination. Analysis of the relationships between alanine levels, branched-chain amino acids leucine, isoleucine, valine, and lactic acid levels.
- Lecture 2. Primary and secondary hyperammonemia, the urea cycle, the connection between the urea cycle and energy metabolism. Causes of ammonia accumulation in the blood. Detoxification and neutralization systems for ammonia.
- Lecture 3. Beta-oxidation of fatty acids, ketogenesis, and lipid metabolism in the human body. The importance of lipid metabolism in energy metabolism. Acquired disorders of fat metabolism in the mechanism of the development of central nervous system pathologies, intoxications, and metabolic acidosis.
- Lecture 4. Glutamic acid. Glutamate excitotoxicity. The mechanism of development of neuroinflammation, oxidative stress, and neuronal cell death. The connection between glutamate excitotoxicity and aspartate metabolism, energy imbalance, and fat metabolism disorders.
- Lecture 5. Changes in the metabolism of aromatic amino acids, synthesis and circulation of neurotransmitters in neuroinflammation. Acquired changes in phenylalanine and tryptophan metabolism. Causes of the development of behavioral, emotional, and cognitive disorders in neuroinflammation.
Cost of the course – 10,000 rubles.
Access to the course is provided for a period of 1 month from the date of purchase.
