Membrane cascade plasma filtration
Preparation for Membrane Cascade Plasmafiltration
The severity of a patient's condition, including the extent of psychoneurological complaints, often directly depends on the level of intoxication load. The total intoxication load comprises endotoxicosis (the sum of all toxic substances synthesized within the body as byproducts of metabolism, along with toxins produced by the gut microbiome) and exogenous intoxication (the toxic load received by the body from external sources).
How the body responds to the intoxication load depends on the compensatory capacity of the detoxification systems (liver, kidneys, gastrointestinal tract, skin, lungs). If the detoxification systems are genetically weak or fail to function due to overload, even a minimal amount of intoxication triggers a response from the cardiovascular system, the immune system, and, of course, the central nervous system.
Detoxification is a foundational stage of working with a patient, without which moving on to rehabilitation measures is pointless. In a number of cases, detoxification mechanisms can be initiated in an outpatient setting (sorbents, hemosorbents, support for the liver's detoxification functions, normalization of bile flow, etc.).
However, there are a number of clinical situations that require rapid detoxification. This is especially significant for weakened and frequently ill patients who respond poorly to medications and experience frequent allergic skin and intestinal reactions. In such cases, we introduce courses of Membrane Cascade Plasmafiltration.
Membrane Cascade Plasmafiltration is one of the extremely important tools used by our physicians in infusion-detoxification therapy regimens. It can be applied at the very beginning of treatment to "cover" antigen-reduction protocols, or it can serve as a final stage — for example, within a protocol for preparing for a stem cell transplant.
Membrane Cascade Plasmafiltration belongs to the methods of extracorporeal hemocorrection (EH). EH is the process of a directed quantitative and qualitative modification of the cellular, protein, water-electrolyte, enzyme, and gas composition of the blood by processing the blood outside the body.
The use of therapeutic Membrane Cascade Plasmafiltration makes it possible to intensively remove from the body both metabolic byproducts and exotoxins, as well as circulating immune complexes (CICs), which underlie the development of pharmacoresistant conditions (unremitting seizure episodes, resistant psychotic states, depression, etc.).
Thus, with the help of Membrane Cascade Plasmafiltration, we achieve:
- Purification of the blood and body tissues by reducing the excess plasma content of proteins, lipids, cholesterol, hormones, antigens, antibodies, and immune complexes; as a result, we obtain an increased sensitivity to medications and a sharp reduction in the neuroinflammatory process.
- Normalization of blood rheology — reduction of blood viscosity and restoration of normal blood supply to all of a person's organs and systems;
- Timely removal of metabolic byproducts from the body through the normal functioning of the liver and kidneys;
- Activation of antioxidant defense factors;
- Strengthening of immunity and reduction of the autoimmune load;
- Activation of regenerative processes
Despite a number of important independent effects of hemocorrection procedures, they attain their greatest efficacy only as part of a comprehensive infusion-detoxification program. In other words, Membrane Cascade Plasmafiltration is not used as a monotherapy and delivers its maximum effect only as part of a therapeutic program prescribed by the attending physician.
